Preparation of porous tri-calcium phosphate ceramic scaffold for bone tissue engineering

نویسندگان

  • Wei Zheng
  • Cheng Yan
  • Wei Fan
  • Clayton Adam
  • Kunle Oloyede
  • Feng Lin
چکیده

Calcium Phosphate ceramic has been widely used in bone tissue engineering due to its excellent biocompatibility and biodegradability. However, low mechanical properties and biodegradability limit their potential applications. In this project, hydroxyapatite (HA) and calcium phosphate bioglass were used to produce porous tri-calcium phosphate (TCP) bioceramic scaffolds. It was found that porous TCP bioceramic could be obtained when 20wt% bioglass addition and sintered in 1400C for 3 h. Significantly higher compressive strength (9.98 MPa) was achieved in the scaffolds as compared to those produced from TCP powder (<3 MPa). The biocompatibility of the scaffold was also estimated. KeywordsTri-Calcium Phosphate; scaffold; Hydroxyapatite;

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تاریخ انتشار 2010